Is amlodipine a cyp?
Score: 4.6/5 (69 votes) Amlodipine is largely metabolized in the liver via the Cytochrome P450 3A4/5. CYP3A4 is the main contributor to amlodipine dehydrogenation. Plasma concentration of this drug depends on metabolic rate which in turn depends on the activity of cytochrome isoenzymes metabolizing ...